Aromatase Inhibitors In Premenopausal Women

More recently aromatase inhibitors ais have come into widespread use. Initially the ais were used alone in postmenopausal patients to prevent disease recurrence.

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Aromatase inhibitors in premenopausal women. Selective anastrozole arimidex letrozole femara exemestane aromasin vorozole r 76713. In postmenopausal women only aromatase inhibitors can greatly reduce oestrogen concentrations hence avoiding stimulation of er positive breast cancer cells. Approximately 11 of patients with breast cancer bca are diagnosed before menopause and because in most of those patients the tumour expresses a hormone receptor treatment with endocrine interventions can be applied in any setting of disease early or advanced.

There are three aromatase inhibitors. Aromatase inhibitors are a class of drug used to prevent cancer recurrence in postmenopausal women with estrogen receptor positive breast cancer. Aromatase inhibitors in premenopausal women with breast cancer.

Anastrozole aromasin chemical name. The state of the art and future prospects. These medications also are prescribed for premenopausal women in combination with ovarian suppression therapy and for men with breast cancer who are unable to take tamoxifen.

Exemestane femara chemical name. Aromatase inhibitors given either for 5 years or for 2 3 years after 2 3 years of tamoxifen produce greater reductions in recurrence than 5 years of tamoxifen alone. Rivizor formestane lentaron fadrozole afema.

The ais interfere with the last enzymatic step of estrogen synthesis in which androgens are converted into estrogens.

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